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Oncogene 2006,25, 56405647

Copper deficiency primarily disrupts lipid homeostasis by impairing the activation of key transcription factors, sterol regulatory element-binding proteins (SREBP-1 and SREBP-2), which regulate fatty acid and cholesterol synthesis [88]

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As for the regions in which significant associations with sensory symptoms were found in the ASD group, the TPJ is implicated in multisensory integration, likely playing a role in higher-level sensory perception and attention processes [62, 63]