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Furthermore, siRNA-mediated knockdown of MyD88, PI3K , and mTOR , but not TAK1 or TBK1, resulted in decreased levels of ATF4 and SLC25A33 proteins, underscoring the role of MyD88-PI3K-mTORC1 signaling in the regulation of ATF4 and SLC25A33 in LPS/IFN--stimulated PMs (Fig

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