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Metabolic applications

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In general, though large cohort studies and countable intervention studies have found a link between maternal fermented foods consumption and reduced risk of pregnancy complications, more in-depth clinical studies with fermented foods intervention among pregnant women would inform preventive strategies for reducing pregnancy-related complications

Additionally, excessive copper may increase autophagic flux through the activation of the Beclin-1 (Wan et al., 2020), autophagy-related gene 5 (Wan et al., 2020), and the adenosine monophosphate-activated protein kinase-mammalian target of rapamycin (Guo et al., 2022a) pathways, promoting the generation of autophagic vesicles by regulating the transcription factor EB (Pea and Kiselyov, 2015)

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