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The absorbed glutamine is subsequently catabolized into the TCA cycle, providing essential energy for cellular functions [29] (Fig

Q., Cropper, E

While MC4R KO mice generally demonstrate a more severe diabetic phenotype, male MC3R KO mice nevertheless do display mild impairments in insulin sensitivity and glucose control, along with increased adiposity (Butler et al., 2000

GSH, synthesized from glutamate, cysteine, and glycine via GCL and GS, serves as the major intracellular antioxidant and a substrate for GPX4, a key enzyme in preventing lipid peroxidation (289)