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Silveira MG, Brunt EM, Heathcote J, Gores GJ, Lindor KD, Mayo MJ Hepatology (Baltimore, Md.) 2010 Jul 52 1 349-59 The 5-D itch scale: a new measure of pruritus

Primary bile acids including chenodeoxycholic acid and cholic acid, with FXR as their the receptor, have distinct effects on cardiac health when compared to secondary bile acids (Fiorucci et al., 2010)