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Although the data are mixed with some studies demonstrating no effect of supplemental vitamin D and/or Ca on bone health (76, 77) there are several well-controlled clinical trials and meta-analyses suggesting there is a synergistic relationship between intake of Ca and vitamins D and K on markers of bone health (i.e., bone mineral density, circulating levels of biomarkers associated with bone health, and risks of fractures) (4447, 78)

Because GSH is proven safe, and is a natural protectant produced by the body, it can be taken orally routinely, on a daily basis, to provide consistently high levels in all cells throughout the body

Xelpros can be used to treat glaucoma or ocular hypertension [341]

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Acknowledgments The authors thank professor Haibo Mu who provided helpful comments for revising the paper