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This intensity gated systemic redox signaling model is illustrated in Figure 6, where the signal is released into the blood stream in response to the high intensity exercise and activates Nrf2 signaling in the contralateral unstimulated muscle, while low intensity muscle stimulation does not meet the threshold to propagate a systemic redox signaling response

Murphy AC, Lalor SJ, Lynch MA, Mills KH

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Dexamethasone-induced oxidative stress enhances myeloma cell radiosensitization while sparing normal bone marrow hematopoiesis

Fragments of double-stranded RNA (dsRNA) stop proteins being made from messenger RNA that contains an identical sequence