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In a 2025 review, after 1,200 mg intravenously twice a week for six weeks, 37.5% of participants reported lighter skin compared with 18.7% in the placebo group, and the effect faded after about six months

baseline NIHSS 12 [8-17]), of whom 394 (79.4%) received EVT and 102 (20.6%) MM

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Interestingly, menadione appeared to be more effective as inducer of the oxidative stress response in phLF than in phBEC

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