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When someone loses 24% of their body weight over 48 weeks, they are not simply burning stored fat

10.1136/bmjopen-2020-047632 29 IzzoR.TrimarcoV.MoneP.AloeT.Capra MarzaniM.DianaA.et al (2022)

This may also reflect an underlying neuroinflammatory process

5e and f)

Natural history and prognostic considerations There are numerous reports on the natural history and prognosis of PBC in terms of clinical, biochemical, histological and treatment response