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All properties that can influence the performance of the above processes determine the final therapeutic effect [122]

Although primarily known as a pro-inflammatory cytokine that binds to cell membrane receptors to potentiate intracellular signaling 45 , eNAMPT can also be taken up by cells such as neurons and increase NAD + synthesis 46

The critical role of glucuronidase treatment has also been emphasized by Ali et al

stage 2 (acceleration in incidence), rapidly increasing incidence and low prevalence

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