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Sodium molecules create a gradient that prevents water from simply diffusing into cells or being lost too quickly through kidneys before circulation stabilizes

Covariates The following variables were collected by standardized questionnaires: age, sex, race/ethnicity, smoking status, alcohol consumption, and physical activity

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Upon stratifying the population based on age and severity of TR, there was no association between moderate-severe TR and 3-year mortality in patients pre-LTx and post-LTx with hazard ratios of 0.744 (95% CI 0.438-1.262) and 0.877 (95% CI 0.517-1.487) respectively