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While Akkermansia is often considered a beneficial microbe in metabolic contexts, in PD its overgrowth might reflect (or contribute to) excessive mucin erosion and gut barrier dysfunction [156]

(PubMed) Shalata A, Mandel H, Dorche C, et al

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Generally, most healthcare providers do not recommend taking these medications together because this combination has not been well studied in clinical trials and is not FDA-approved for safety and efficacy