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YT: Writing original draft, Writing review and editing

1 Introduction Cancer is a global health concern, with an estimated 19.3 million new cases and almost 10 million deaths reported in 2020 (Sung et al., 2021)

In obesity, circulating fasting glucose levels were found to be associated with the extent of brain atrophy and amyloid accumulation (Matulewicz and Karczewska-Kupczewska, 2016

Although current treatments such as chemotherapy, radiation therapy, and surgery have improved patient outcomes, they are frequently limited by severe side effects, drug resistance, and damage to healthy tissues

Protein group intensities were median normalized and missing values were imputed using a Gaussian distribution centered on the median with a downshift of 1.8 and width of 0.3 (relative to the standard deviation)