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The question of whether genetic polymorphisms of CYP2D6 can affect treatment outcome in patients with early postmenopausal breast cancer has been a matter of debate, the necessity of genotyping to guide tamoxifen therapy is even another ongoing argument [74, 76, 77]

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In the future, in-depth analysis of the ASCT2 3D structure using structural biology techniques and an in-depth understanding of the interaction mechanism between ASCT2 and inhibitors will help to optimize the structure of inhibitors and improve their efficacy

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Those managing chronic fatigue, illness recovery, or intense athletic training may benefit from weekly sessions initially, tapering to a maintenance schedule once optimal levels are established