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In addition, glycolysis (mainly involving HK2 activity) is involved in the regulation of inflammatory vesicle activation and to play a crucial role in the activation of NLRP3 (166)

Reprod Health 18 , 207 (2021)

H.GundersenV

DKD patients exhibit significant structural dysbiosis of gut microbiota, characterized by decreased abundance of beneficial bacteria producing short-chain fatty acids (SCFAs) and increased abundance of harmful bacteria generating uremic toxin precursors (12)