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Smoking affects the heart long before symptoms appear. Each cigarette delivers chemicals that enter the bloodstream within seconds, reaching the heart and blood vessels almost immediately. These substances damage the inner lining Smoking: A Direct Hit to the Heart Every puff of a cigarette is a direct challenge to your cardiovascular system. Beyond the lungs, the chemicals in tobacco smoke enter your bloodstream 26 Health Effects of Smoking on Your Body Nicotine Blood, Urine, and Saliva Tests: What to Expect Can Doctors Tell if You Smoke From a Blood Test?
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