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Gastrointestinal side effects are the primary clinical concern: nausea (44%), diarrhea (30%), vomiting (24%), and constipation (24%) are common, particularly during dose escalation

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[30] In 2001, at University of Calgary Leong, et al, published a paper that included a video clip showing the disruption of tubulin-neurofibril interaction that represents how mercury, and only mercury, as opposed to other metals, can cause synaptic neurodegeneration by destroying neuron growth cones

In vivo studies showed that green tea catechins increase total plasma antioxidant activity [77, 78]