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Therefore, to establish a realistic and efficient workflow for unknown biological samples, a representative pooled sample was first analyzed in a qualitative screening run to estimate the baseline concentrations of all analytes

Because prognostic factors are treatment dependent, improvements in therapy may diminish or abrogate the significance of any of these prognostic factors

In mouse models with specific knockouts of the MLL4 and ALOX12B genes, skin pathological changes similar to ichthyosis, including epidermal hyperplasia and desquamation, were observed (141)

Targeted inhibition of PTDSS1 expression results in increased ubiquitination of SLC3A2 and inhibition of GSH synthesis, thereby inducing oxidative stress in tumor cells, activating the PINK1/Parkin/MFN2 mitophagy pathway, and ultimately promoting tumor cell apoptosis and ferroptosis (Fig

And so on and so forth