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Chlamydia pneumoniae relies on host glutathione for its growth and induces integrated stress response-mediated changes in macrophage glutathione metabolism

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In a dynamic gastrointestinal simulator mimicking human digestion, pClc at 1:250 (1:10,000 relative to flour), following activation by simulated gastric fluid, reduced GIP by 99% in the stomach phase, while remaining inactive during oral and intestinal phases, consistent with its pH-dependent profile

We further conducted pre- and post-attachment neutralization assays to investigate the viral entry inhibition activities of these two antibodies

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