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The most exciting part of this work, said McCall, is that it demonstrates a new therapeutic approach with the potential to be disease-modifying for IPF. Analysis of scRNA-seq data from patients with IPF and a mouse model of repeated injury to lung epithelium revealed persistent activation of hypoxia-inducible factor (HIF) signaling in fibrosis-associated aberrant (abnormal) epithelial cells

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It is not recommended in patients with a history of thyroid tumors and endocrine neoplasias

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Many patients notice improved focus and reduced anxiety within 3-7 days