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In cases of PCA accumulation due to a decrease in the expression of phzM , the excess PCA is directly converted to 1-hydroxyphenazine by the action of the phzS enzyme

For these two patients, CVS was triggered by stress and low dose of amitriptyline was efficient in these two patients once the study the first year of treatment with CoQ10 was achieved

a large superfamily of related but distinct enzymes

Moreover, the association of specific markers of SnCs and senolytic drugs could be a great combination in the treatment of age-related diseases

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