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Because the heart muscle derives the vast majority of its energy from the beta-oxidation of fatty acids, a depletion of L-Carnitine severely compromises the heart's ability to sustain this compensatory effort

doi: 10.3389/fnut.2025.1664866 Received 13 July 2025 Accepted 20 October 2025 Published 04 November 2025 Volume 12 - 2025 Edited by Bingzi Dong, The Affiliated Hospital of Qingdao University, China Reviewed by Karem Salem, Fayoum University, Egypt Shivmurat Yadav, University of Oklahoma Health Sciences Center, United States Updates Copyright 2025 Shang, Wang, Du, Zhang, Duan, Leslie, Lix, Kan and Yang