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Isoliquiritigenin limits inflammasome activation of macrophage via docking into Syk to alleviate murine nonalcoholic fatty liver disease

Aoi W, Ogaya Y, Takami M, et al

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Since the neonatal antioxidant capacity is weak and phototherapy may increase oxidative stress in infants with neonatal jaundice, this may reduce the levels of antioxidants, such as reduced glutathione and ascorbic acid (72), leading to an imbalance of the oxidative and antioxidant defense system in the neonatal body (73,74), with alterations of the erythrocyte membrane structure and ensuing hemolysis (41)

hydrogen bonding predominates as the primary driver, with hydrophobic and - stacking serving auxiliary structural roles