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Expected weight loss timelines For semaglutide at 2.4 mg maintenance, expect approximately 5% body weight loss by month 3, 10% by month 6, and 15% by month 12-16

Acknowledgements The study was funded by InBrain Pharma, France, a spin-off of the research academic team UMR-S 1172 (University of Lille, INSERM, University Hospital of Lille), which delegated the promotion of the study to the University Hospital of Lille, France

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(1) The authors suggested that both formulations appeared to produce a positive response regarding hair growth in the animals

This pathway gene list formed the basis of the hypoxia- associated network constructed based on published pathway graphs (Supplementary Table 3 and Supplementary Figs