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Bidlack, PhD Estheany Romn Pagn, Universidad Ana G

10.1017/S0007114509276446 83 PfeifferC.BachM.BauerT.Campos da PonteJ.SchmigE.GrndemannD

Barba, E

These metabolites are produced by the gut microbiota upon the absorption of specific substances and function as signaling molecules and reaction substrates during metabolic processes, playing a crucial role in the onset and progression of lung diseases, including lung infections

Although the MISEV guidelines have improved transparency and rigor in EV reporting, they primarily address minimal reporting standards and do not yet resolve critical issues related to inter- and intra-batch heterogeneity, potency assessment, or clinical-grade validation (MISEV guidelines