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Metformin also disrupts the growth and metastasis of NSCLC by inhibiting the activity of the miR-381-YAP-Snail axis (70)

Discussion EZH2, a histone methyl transferase subunit of a Polycomb repressor complex, is recurrently mutated or highly expressed in several cancers, including ACC [10] and its deregulation is associated with tumor proliferation and worse patient outcomes [35]