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Smad7 gene transfer therapy: therapeutic applications beyond colonic fibrosis

More importantly, DHODH operates in parallel with mitochondrial GPX4 to inhibit ferroptosis, and this is independent of cytosolic FSP1 and GPX4 [53]

hanmipharm.com (2025)

At the rear, the uropod concentrates ERM (ezrin, moesin and radixin) proteins that link membrane components with the cortical actin cytoskeleton and adhesion molecules like CD44 and ICAMs (intercellular adhesion molecules) interacting with integrins, including LFA-1 [98, 99]