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Cell viability was calculated as a ratio of the absorbance in the treated group to that in the control group, which consisted of cells cultured under normal conditions without OGD/R exposure

3.5 Effect of Vit D on T-cells in MS As part of adaptive immunity, Vit D directly affects T lymphocytes by inhibiting their proliferation at the G1 a to G1 b cell cycle phase (117)

Simultaneously, healthy cells are better able to multiply resulting in a stronger immune system and an overall improved immune response

mean SEM) compared with MDMA (4.1 0.4 h

Data availability The cryo-EM data generated in this study have been deposited in the PDB and in the EM data bank under accession codes 8A1R and EMD-15084, respectively