Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide monosulfo is azide-activated fluorescent dyes

monosulfo is azide-activated fluorescent dyes for chemoselective labeling and detection of alkyne-tagged molecules

& Polasek-Sedlackova

TCO (trans-cyclooctene) is a strained alkene used in click chemistry for bioorthogonal reactions like iEDDA (inverse electron-demand Diels-Alder)

383 SMILES OCCOCCCC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

650Ex/670Em) is a sulfonated derivative of its parent dye

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide monosulfo is azide-activated fluorescent dyesSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine