horse on b12 injections Vetoquinol Vitamin 5000 30mL How to administer vitamin B12

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In contrast, there is some evidence of an enhancement of the maximum absorption via intrinsic factor, by up to a factor of 2, when the vitamin B12 is accompanied by food, but this is not consistently observed and probably only applies when the food quantity and vitamin B12 dose are sufficient to slow the passage of the vitamin B12 through the small intestine enough (about three hours or more) to allow each intrinsic factor receptor to absorb two molecules of vitamin B12 from the oral dose rather than one

I've also read about once the process is overridden by saturation of B12 there's no going back to the natural process that was failing anyway

Notice its a caution-and-compensation argument, not a the effect wears off argument

Chronic hyperglycemia damages small blood vessels (microvascular disease) and accelerates atherosclerosis (macrovascular disease)