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However, our approach is a significant advance on these earlier methods, for the following reasons: snap-freezing of samples followed by reaction with IAM-TPP/IAM enables us to trap and stablise all reactive sulfur species simultaneously through their nucleophilic reactions to generate stable products, rather than leaving labile moieties that may be modified during sample workup

The FDA review is, in many ways, a public catch-up to a standard we already hold ourselves to

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It was less than 48 hours I thought I pulled a neck muscle and then the following day it felt like a severe muscle pulled in my shoulder blade

During the metabolomic in silico analysis, certain compounds posed a challenge for the software due to their inherent tendency to produce fragments very easily