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1 CagriSema is a fixed-dose combination of a long-acting amylin analogue, cagrilintide 2.4 mg, and the GLP-1 receptor agonist, semaglutide 2.4 mg

Further examination showed that GDF11 acts directly on neurons via phosphorylation of SMAD2/3 and that the autophagic process is necessary for the enhancement of neuronal activity mediated by GDF11