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Heart disease and stroke statistics-2016 update: A report from the american heart association

doi: 10.1038/ng.2953 22 FaillotSAssieG

This binding activates the expression of key antioxidant genes, including heme oxygenase-1 (HO-1), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), and NAD(P)H quinone oxidoreductase 1 (NQO1) ( Figure 3 ) (58, 59)