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By secreting active uricase, these engineered bacteria successfully lowered serum uric acid (SUA) levels in rats, offering a novel solution to a gap in current treatment strategies, which primarily focus on reducing uric acid production rather than enhancing its excretion

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Serine biosynthesis is a metabolic vulnerability in FLT3-ITD-driven acute myeloid leukemia

Additionally, it was found that S100A9 levels, as determined by liquid biopsy, were a significant predictor of radiation response in a cohort of brain-metastatic NSCLC, breast cancer, and melanoma patients

MG carried out bioanalytical assay development and validation followed by sample analysis and provided bioanalytical data for evaluation