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Interestingly, methylxanthine derivatives, including CAF, PTXN and theophylline, and the family 18 chitinases show a similar form of binding and have a common position for docking revealed by X-ray diffraction analysis [23]

Activation of TLR4 has been found to increase the risk of SLE development, and bacterial components, including lipoteichoic acid (LTA), are also known to induce SLE (Liu et al