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Gonzlez-Moles, M., Aguilar-Ruiz, M

Proposes a mechanistic classification framework for pain in cirrhosis (nociceptive, neuropathic, nociplastic) and argues for phenotype-directed treatment approaches

This led to a move away from using albumin in the ICU Saline versus Albumin Fluid Evaluation (SAFE) trial -- 2004 NEJM RCT of 4% albumin vs normal saline in 7,000 critically-ill patients, showing no mortality difference

A double-blind randomised, multi-centre clinical trial to evaluate the efficacy and safety of two doses of etomoxir in comparison to placebo in patients with moderate congestive heart failure: The ergo-study