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Metformin reduces asymmetric dimethylarginine and prevents hypertension in spontaneously hypertensive rats

10.1016/s0021-9258(17)41868-0 J

Due to the fact that CD38 is implicated in both cardiovascular disease and depression, it may represent a potential mechanism for the comorbidity between CVD, particularly myocardial infarction and HF, and depression

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