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It remains to be investigated whether changing the amino acid sequence of ROXY9 into the sequence of class I GRXs at the discussed positions will be sufficient for a gain of function with respect to oxidoreductase activity, or whether other structural perturbations in the protein are responsible for its dysfunctionalized oxidoreductase activity

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10.1021/np060509t 64 IsakaM.SrisanohU.LartpornmatuleeN.BoonruangprapaT

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