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Although carnitine is indeed taken up in the intestine, research has shown that a large proportion of L-carnitine supplements is directly excreted or quickly cleared by the kidneys in the urine

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For people with serious kidney disease undergoing hemodialysis: Doses of 0.64-3 grams or 10 mg/kg of L-carnitine has been used daily for 3-52 weeks

55 Conflicting results have been reported regarding the efficacy of ALC for CIPN, with one study reporting worsening of neuropathic pain in CIPN patients with ALC