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The dysregulation of energy homeostasis leads to the activation of key oncogenic pathways and transcriptional programs, such as the ones controlled by HIF, mTOR, and PI3K

J Clin Invest 117(5):14221431 Simpson JB, Sekela JJ, Carry BS, Beaty V, Patel S, Redinbo MR (2023) Diverse but desolate landscape of gut microbial azoreductases: a rationale for idiopathic IBD drug response

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Only the patients with cholesterol type of gallstone were included by classification as typical cholesterol by visual inspection of cut-surface of gallstones and when necessary, by chemical analysis in the laboratory 37,38

In a recent study published in Science Advances , we showcased a platform for the mechanistic study of insulin signaling and resistance using in vitro human pluripotent stem cell (hPSC)-derived adipocytes