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DOI: 10.1016/j.jnutbio.2020.04.007

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

Oxidative stress is a major factor that leads to cell aging

Treatments that transiently disrupt the skin barrier microneedling , laser resurfacing , and chemical peels create a window in which topically applied actives penetrate far more effectively than they do through intact skin