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Given that some women may already suffer from IDA prior to pregnancy due to factors such as dietary imbalance and unhealthy lifestyle habits (14, 23, 24), and their condition tends to worsen during pregnancy, thereby increasing pregnancy-related risks, based on existing pharmacological experimental foundations (4, 25, 26), we adopted a method of feeding rats with a simple iron-deficient diet to induce IDA before mating, thus establishing a pregnant rat model under IDA conditions

Some animal studies, such as one involving a segmental bone defect in rabbits (Sebecic et al., 1999), explored its local application

In another independent study, incidence of mood and anxiety disorders after the onset of IBS were around 40 and 23% respectively

(2015): in studies of drugs approved between 2010 and 2012, just 45 percent of trial participants in small molecule trials were women, but they represented 65 percent of participants in biologic trials (based on Drugs@FDA data)

The 2025 RCT: dermaroller plus copper peptide vs dermaroller alone The study followed patients with facial acne scars over 16 weeks using the Goodman and Baron qualitative and quantitative acne scar index