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658 This association appears most frequently with heavy alcohol consumption, and the effect of light-to-moderate drinking remains unclear

The uptake of iron (transferrin (TF)), non-transferrin-bound iron (free iron), heam, and hemoglobin, storage (ferritin), utilization (nuclear receptor coactivator 4 (NCOA4)) or efflux (solute carrier family 40 member 1 (SLC40A1/ferroportin-1 (FPN))) are important to maintaining intracellular iron homeostasis (Fig