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Daratumumab has direct and indirect anti-cancer activity by binding to CD38, inducing direct apoptosis of tumor cells and triggering complement-dependent cytotoxicity (CDC), antibody-dependent cell-mediated cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP) [64]

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Recently many researchers have attempted to evaluate the potential role of the deficiency in childhood neurological syndromes like Autistic spectrum and Attention Deficit Hyperactivity Disorder