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Thus, the effective growth rate increases monotonically with concentration up to C 0 , implying that the optimal protocol must maintain C ( t ) C 0 to keep the population at carrying capacity N max (Figure 5b)

Toxins leave the liver via bile, which flows into the intestines and is excreted through stool, or they are filtered through the kidneys and excreted in urine

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With regard to distribution , for drugs such as diazepam 1 and penfluridol 5 that are substantially distributed into adipose tissue, greater adiposity is associated with greater storage of the drug in lipid reservoirs, and hence greater availability of the drug for return to blood as blood levels fall due to metabolism