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Acetyl l-carnitine is more effective for improving cognitive and neurological function as the acetyl group allows the compound to cross the blood-brain barrier with a lot greater efficiency than l-carnitine alone

FIGURE 3 The first choline-TMA lyase inhibitor, DMB, was identified by Wang and colleagues, which is shown to non-lethally inhibit distinct microbial TMA lyases, and reduce TMAO levels in mice fed a high-choline or L-carnitine diet (Wang et al., 2015)

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Larsen PR, Davies TF, Hay ID