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Foller M, Kasinathan RS, Koka S, Lang C, Shumilina E, Birnbaumer L, et al

On the other hand, the regulatory class primarily comprises of TFs ( AREB, AP2/ERF, NAC, bZIP, MYC , and MYB ), signaling protein kinases mitogen activated protein kinases (MAPK), calcium-dependent protein kinases (CDPK), receptor protein kinases and protein phosphatases (phosphoesterases and phospholipase), which triggers signal transduction and expression of genes during stress responses (Wani et al., 2013)

For example, patients prone to DILI may benefit from lower doses and slower upwards titration to avoid the hepatotoxic effects

For example, Vitamin C, Glutathione, and Zinc can strengthen immunity

Immunological factors play a prominent role in the development of this disease (204)