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doi: 10.1016/j.jes.2020.08.030, 136 LiD.ZhouC.WangS.HuZ.XieJ.PanC.et al

Recent reports have shown that system x c - activity promotes cancer cell dependency on glucose 14, 16, 24 , although the mechanism by which system x c - promotes glucose deprivation-induced cell death remains disputed

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Second, developing synergistic therapeutic strategies-inhibiting the SLC43A2 transporter can diminish the methionine advantage of tumor cells, thereby restoring the anti-tumor function of T cells