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Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease

The relative concentration of each individual regulator, their individual affinities derived from PL motif recognition and secondary recognition by VPS35, and additional low affinity binding to features of the local environment such as lipids, membrane geometry, F-actin and non-Retromer-interacting proteins, will provide the avidity that defines their enrichment and residency at the Retromer-demarcated retrieval sub-domain

MitoQ supplementation augments acute exercise-induced increases in muscle PGC1 mRNA and improves training-induced increases in peak power independent of mitochondrial content and function in untrained middle-aged men

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