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Description

Importance of the alternative NF-kappaB activation pathway in inflammation-associated gastrointestinal carcinogenesis

(PubMed) Higdon JV, Liu J, Du SH, Morrow JD, Ames BN, Wander RC

2936619-43-9 Appearance Solid Molecular Weight 362.47 (free base) Formula C 22 H 26 N 4 O.xC 6 H 8 O 7 Color White to off-white SMILES O=C(CC(C(O)=O)(CC(O)=O)O)O.O=C(N1CCC1)C2=CN3C(C)=C(C)N=C3C(NCC4=C(C)C=CC=C4C)=C2.[x] Synonyms JP-1366 citrate Shipping Room temperature in continental US

These results validated that Fer-1, a ferroptotic inhibitor, could reverse IMP-366-induced upregulation of necroptotic markers and the morphological changes associated with necroptosis (Fig